In some ways, the Tottenham Hotspur starting lineup kind of picks itself. With as many as 16 players either out injured or considered doubtful, Spurs boss Thomas Frank does not have a ton of options. This is the case at multiple position groups. You don’t want go into a big time rivalry match banged up, and especially so for the road edition, but here we are.
Tottenham must make do with what they have. Arsenal have some injuries to deal with as well.
North London Derby FYIs
Kickoff: Nov 23, 2025, at 430pm UK at Emirates Stadium
Full Injury Updates: Tottenham Part 1 Tottenham Part 2 Arsenal FC
Team News: Tottenham Arsenal FC
Starting XI Predictions: Arsenal FC Tottenham
Google Result Probability: Arsenal FC 69% Draw 19% Spurs 12%
PL Position, Form Guide: Arsenal FC 1st, 26 pts WWWWD Spurs 5th, 18 pts WLWLD
Nevertheless, this will be the standout fixture of the Premier League weekend.
Tottenham Hotspur Predicted Starting XI at Arsenal
Guglielmo Vicario; Destiny Udogie, Cristian Romero, Micky van de Ven, Djed Spence; Rodrigo Bentancur, Pape Matar Sarr; Mo Kudus, Xavi Simons, Brennan Johnson; Richarlison
Paul M. Banks is the Founding Editor of The Sports Bank. He’s also the author of “Transatlantic Passage: How the English Premier League Redefined Soccer in America,” and “No, I Can’t Get You Free Tickets: Lessons Learned From a Life in the Sports Media Industry.”
He currently contributes to USA Today’s NFL Wires Network. His past bylines include the New York Daily News, Sports Illustrated and the Chicago Tribune. His work has been featured in numerous outlets, including the Wall Street Journal, Forbes, the Washington Post and ESPN.